This Week in Pediatric Oncology

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TWiPO #64 - Interview with Dr. Lars Wagner

July 17th, 2017

It’s an exciting time to be part of the childhood cancer research community, and this interview was focused on career advice for those interested in childhood oncology and research. The availability of genomic profiling of tumors, targeted agents and the development of new immunotherapies are increasing the opportunities available to patients today. This lively discussion addresses the importance of preclinical data, predictive biomarker studies and the measurement of responses, with specific references to Dr. Wagner’s experience with studying irinotecan.   Dr. Wagner also answered questions about radiomics and how this imaging trend can provide more insights for enhanced radiology reporting.

Please send questions and comments to TWiPO@solvingkidscancer.org 

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TWIPO # 63 - INTERVIEW WITH DR. JAVIER BLANCO

July 17th, 2017

Co-Hosts Dr. Timothy Cripe and Dr. Randal Olshefski (Nationwide Children's Hospital), interview Dr. Javier Blanco, Associate Professor at the Department of Pharmaceutical Sciences at SUNY Buffalo, about the late effects of chemotherapy.  In this podcast, the participants discuss the role that chemotherapy, such as doxorubicin and other anthracycline drugs, often play in increasing cardio-toxicity.

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TWiPO #62 - Interview with Dr. Uri Tabori

May 25th, 2017

TWiPO hosts and cohosts interview Dr. Uri Tabori about the challenges that are unique to pediatric brain tumors, and how preventative treatment and early diagnosis can be largely beneficial.  

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TWIPO #61 - Interview with Dr. Matthew Breen

May 25th, 2017

TWIPO hosts and cohosts interview Dr. Matthew Breen, NC State Veterinary Medicine, to explore the question "Can dogs teach us new tricks when it comes to cancer treatment?"

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TWIPO #60 - Interview with Dr. Josua Mendell

May 25th, 2017

TWIPO hosts and cohosts interview Dr. Joshua Mendell, UT Southwestern Medical Center, who shares his knowledge with regard to the relationship between innate RNA biology and how it influences human disease.  

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TWiPo #59 ~ Interview with Dr. Sajid Qureshi

October 17th, 2016

Host Dr. Timothy Cripe and co-Host Nilay Shah interview Dr. Sajid Qureshi, a professor of Pediatric Oncology at the Tata Memorial Center, Mumbai, India. Dr. Qureshi is an Executive Committee Member of the International Society of Pediatric Surgical Oncology (IPSO). In this episode Dr. Qureshi provides a fascinating, first-hand glimpse into the successes and challenges of delivering quality care to larger, as well as remote, pediatric cancer populations. The episode concludes with Dr. Qureshi's thoughts on how international research collaboration could provide access to relapsed children worldwide.

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TWiPO #58 ~ Interview with Dr. Damon Reed

October 17th, 2016

TWiPO Host Dr. Timothy Cripe, with co-hosts Dr. Nilay Shah and Dr. Bhuvana Setty welcome Dr. Damon Reed, Director of the Adolescent and Young Adult Program at Moffitt Cancer Center and Leader of the Pediatric Cancer Foundation's pediatric phase I consortium, the Sunshine Project. Dr. Reed shares his view points on how we can improve and accelerate the current trajectory with regard to pediatric therapy development. 

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TWIPO # 57 Interview with Dr. Elizabeth Lawlor

October 6th, 2016

TWIPO hosts Dr. Timothy Cripe and Dr. Nilay Shah (Nationwide Children's Hospital) along with guest host Dr. Ryan Roberts (Nationwide Children's Hospital), interview Dr. Elizabeth Lawlor who is a Professor of Pediatric Oncology at University of Michigan and the Director of the Cancer Biology Training Program at University of Michigan Health System. Dr. Lawlor, a Ewing Sarcoma specialist, discusses new approaches to the cellular eco-system of tumors and provides commentary on the growing landscape for women in science.

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TWIPO #56 ~ Interview with Dr. Mark Hatley

September 6th, 2016

On today's podcast, TWIPO host Dr. Timothy Cripe (Nationwide Children’s Hospital) and co-host Dr. Ryan Roberts (Nationwide Children’s Hospital) interview Dr. Mark Hatley (St. Jude Children's Research Hospital). Dr. Hatley discusses how he got into the field of Biological Chemistry in Oncology. Also Dr. Hatley gives an indepth explaination about his research in G-Proteins.

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TWiPO #55 ~ Interview with Dr. Chrystal Louis

June 3rd, 2016

On this episode of TWiPO podcast Dr. Timothy Cripe (Nationwide Children’s Hospital) and co-host, Dr. Nilay Shah (Nationwide Children’s Hospital) and Dr. Keri A. Streby (Nationwide Children's Hospital) interview Dr. Chrystal Louis (Assistant Professor, Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine.) Dr. Louis talks to the hosts about her role in both the academic and industry side of oncology. 

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TWiPO #54 ~ Interview with Dr. Kim Kramer

June 3rd, 2016

On today's TWiPO Podcast host Dr. Timothy Cripe (Nationwide Children’s Hospital) and co-host, Dr. Nilay Shah (Nationwide Children’s Hospital) interview Dr. Kim Kramer (Pediatric Oncologist of Memorial Sloan Kettering.) In this interview they discuss a new cutting edge therapy for treating brain tumors, which involves targeting the tumor intravenously just like any other tumor.

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TWiPO #53 ~ Interview with Linda McAllister-Lucas

April 13th, 2016

On today's podcast TWiPO host Dr. Timothy Cripe (Nationwide Children’s Hospital) and co-hosts, Dr. Nilay Shah (Nationwide Children’s Hospital) and Dr. Robyn Dennis (Nationwide Children’s Hospital) Interview Dr. Linda McAllister-Lucas (Chief of Service, Hematology/Oncology of Children's Hospital of Pittsburgh, Associate Professor of Pediatrics, University of Pittsburgh School of Medicine. In their discussion Dr. McAllister-Lucas talks about her research on MALT1 Lymphoma and how this research could advance the field of oncology 

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TWIPO #52 ~ Interview with Dr. James Geller

December 9th, 2015

On this TWiPO episode hosts, Dr. Timothy Cripe and Dr. Nilay Shah (Nationwide Children’s Hospital) interview Dr. James Geller (Medical Director at Kidney and Liver Tumors Program, Co-Medical Director at Retinoblastoma Program, Associate Director at Global Cancer Programs, Associate Professor at UC Department of Pediatrics.) Dr. James Geller was one of the original TWiPO members back in 2010. Today Dr. Geller talks about the battle to get access to potential drugs (Ex. Lorvotuzumab [IMGN901]) that can be beneficial to treating pediatric cancers.

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TWIPO #51 ~ Interview with Dr. Gregory Armstrong

November 2nd, 2015

This week in pediatric oncology TWiPO hosts Dr. Timothy Cripe, Robyn Dennis, MD, Dr. Nilay Shah interview Dr. Gregory Armstrong (Associate Professor in  the Department of pediatrics at the University of Tennessee health science center, Associate member of in the department of epidemiology in cancer control in Saint Jude's Children's Research Hospital, Director of CNS tumor after completion of therapy clinic at Saint Jude). Dr. Armstrong and hosts discuss the Childhood Cancer Survival Study (CCSS) and the advancements we have made in the field of oncology. Along with problems that they are working to solve.

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TWIPO #50 ~ Interview With Dr. Jonathan Finlay

May 8th, 2015

In this most recent TWiPO podcast hosted by Dr. Timothy Cripe (Nationwide Children’s Hospital), he interviews Dr. Jonathan Finlay (Program Director of Neuro-Oncology at Nationwide Children’s Hospital) about sparked in research interest in brain tumors. One of Dr. Finlay’s mentors, helped launch a new treatment, which was able to rescue a proportion of newly diagnosed children who failed conventional chemotherapy, radiation, and surgery. That novel treatment is now a growing method of treating medulloblastoma.

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TWIPO #49 ~ Interview With Dr. Robin Norris

April 20th, 2015

TWiPO host Dr. Timothy Cripe (Nationwide Children’s Hospital) and TWiPO co-host Dr. Nilay Shah (Nationwide Children’s Hospital) interview Robin Norris, MD, who is a pediatric oncologist and the Director of the Pediatric Developmental Therapeutics Program, Division of Pediatric Hematology and Oncology, at University Hospitals Rainbow Babies & Children's Hospital. Dr. Norris discusses the struggles that adolescents and young adult with cancer face and discusses her involvement in creating an antibody against TEM-1 in order to stop the metastasis of tumors.

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TWIPO #48 ~ Interview With Dr. Michael D. Hogarty

April 20th, 2015

TWiPO host Dr. Nilay Shah (Nationwide Children’s Hospital) interviews Dr. Michael D. Hogarty, MD, an attending physician in the Division of Oncology at The Children's Hospital of Philadelphia. Dr. Hogarty recalls his efforts in finding a new way of tackling neuroblastoma by sending 17,000 tumor samples around the world. In this short interview, he discusses his current work in the lab, which involves testing the MYC gene found in children with high-risk neuroblastoma.

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TWIPO #47 ~ Interview With Dr. Hiro Shimada

March 30th, 2015

TWiPo co-hosts Dr. Keri Stretby (Nationwide Children’s Hospital) and Dr. Nilay Shah (Nationwide Children’s Hospital) interview Hiroyuki Shimada, MD, PhD, Professor of Clinical Pathology at the Children’s Hospital of Lost Angeles. Dr. Shimada developed the Shimada neuroblastoma classification system for neuroblastoma, which was the basis of The International Neuroblastoma Pathology Classification and now The International Neuroblastoma Risk Group classification system.

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TWIPO #46 ~ ANR Recap: Interview With Dr. Sue Cohn

March 30th, 2015

TWiPO host Dr. Nilay Shah (Nationwide Children’s Hospital) interviewed Susan L. Cohn, MD, a Professor of Pediatrics, Dean of Clinical Research at the University of Chicago at the ANR meeting in Cologne, Germany last year for this episode of This Week in Pediatric Oncology. Dr. Cohn is a highly respected expert in pediatric cancers and blood diseases. She is a leading authority on neuroblastoma and actively researching several aspects of neuroblastoma. Her research has received generous support from the National Institutes of Health/National Cancer Institute and the National Institute of Neurological Disorders and Stroke. Dr. Shaw and Dr. Cohn discuss the future of neuroblastoma research and clinical trial design to create more effective treatment options for children with high-risk disease.

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TWIPO #45 ~ Immunotherapy Vaccine for Immunotherapy Vaccine for High-Grade Gliomas

November 18th, 2014

In the most recent episode of This Week in Pediatric Oncology, co-hosts Dr. Nilay Shah (Nationwide Children’s Hospital), Dr. Timothy Cripe (Nationwide Children’s Hospital), and Dr. Lionel Chow (Cincinnati Children’s) discuss the promising results of a study published in the July issue of Journal of Clinical Oncology among children with an aggressive brain tumor after receiving immunotherapy. To see a summary of the study, click here

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