This Week in Pediatric Oncology

TWIPO #42 ~ Advances in Neuroblastoma Research Meeting Recap: Interview With Frank Berthold

New York – This Week in Pediatric Oncology presents the third and final interview from the recent Advances in Neuroblastoma Research meeting, which was held in Cologne, Germany, in May. Co-hosts Dr. Nilay Shah (Nationwide Children’s Hospital) and Dr. Keri Stretby (Nationwide Children’s Hospital) talk with Frank Berthold, ANR2014 Local Chairman, to discuss meeting highlights in the short, 18-minute interview.  

TWIPO #41 ~ Advances in Neuroblastoma Research Meeting Recap: Advances in Understanding MIBG Therapy

New York – This Week in Pediatric Oncology presents the second in a series of interviews from the recent Advances in Neuroblastoma Research meeting, which was held in Cologne, Germany, in May. Co-hosts Dr. Nilay Shah (Nationwide Children’s Hospital) and Dr. Keri Stretby (Nationwide Children’s Hospital) discuss MIBG therapy in treating children with high-risk neuroblastoma with Dr. Kate Matthay (UCSF Benioff Children's Hospital) and Dr. Gregory Yanik (C.S. Mott Children’s Hospital at the University of Michigan). In this 45-minute interview, both Drs. Matthay and Yanik, who have conducted extensive research in MIBG throughout their long careers, share their perspectives on what’s going on in the field now and opportunities to improve the therapy in the future.

TWIPO #40 ~ Advances in Neuroblastoma Research Meeting Recap: Advances in Understanding MYCN

New York – This Week in Pediatric Oncology presents the first of a series of interviews from the recent Advances in Neuroblastoma Research meeting, which was held in Cologne, Germany, in May. Co-hosts Dr. Nilay Shah (Nationwide Children’s Hospital) and Dr. Keri Stretby (Nationwide Children’s Hospital) caught up with two pediatric oncologists who’ve made significant advances in neuroblastoma research. In this 25-minute interview, Dr. Robert Seeger (Children's Hospital of Los Angeles) and Dr. Garrett Brodeur (Children’s Hospital of Philadelphia) discuss how the discovery of the MYCN gene 30 years ago has helped scientists better understand neuroblastoma and impacted treatment options.

TWIPO #39 ~ Declining Childhood Cancer Mortality & CAR123 T-cells

New York, NY -- In the most recent episode of This Week in Pediatric Oncology (TWiPO), the first podcast focusing on pediatric cancer research, co-hosts Dr. Timothy Cripe (Nationwide Children's Hospital), Dr. Robyn Dennis (Nationwide Children's Hospital), Dr. Andy Kolb (A.I. Dupont) and Dr. Lionel Chow (Cincinatti Children's) discuss two recent papers on the declining mortality rate in childhood and adolescent cancers and a pre-clinical study using CAR123 T-cells.Saar Gill, Sarah K. Tasian, Marco Ruella, Olga Shestova, Yong Li, David L. Porter, Martin Carroll, Gwenn Danet-Desnoyers, John Scholler, Stephan A. Grupp, Carl H. June, and Michael Kalos. Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor–modified T cells. Blood. 2014, 10, April. http://www.ncbi.nlm.nih.gov/pubmed/24596416

TWIPO #38 ~ Interview with John Goldberg, MD, on Phase I Clinical Trials

March 11, 2014New York, NY -- This Week in Pediatric Oncology (TWiPO), the first podcast focusing on pediatric cancer research, announced that John Goldberg, MD, from The Sylvester Comprehensive Cancer Center at the University of Miami, is a featured guest on its most recent episode. In this episode, Dr. Golberg talks about the challenges of phase I pediatric cancer clinical trials with hosts Dr. Tim Cripe (Nationwide Children's Hospital), Dr. Robyn Dennis (Nationwide Children's Hospital), and Mark Ranalli, MD (Nationwide Children's Hospital).Dr. Goldberg is an Assistant Professor of Pediatrics and the Director of the Pediatric Oncology Early Phase Clinical Trials Program at The Sylvester Comprehensive Cancer Center, the University of Miami.

TWIPO #37 ~ Interview with Patrick Brown, MD, on Infant Leukemia

February 26, 2014New York, NY -- This Week in Pediatric Oncology (TWiPO), the first podcast focusing on pediatric cancer research, announced that Patrick Brown, MD, from The Sidney Kimmel Comprehensive Cancer Center, is a featured guest on its most recent episode. In this episode, Dr. Brown  talks about treating infant leukemia and the challenges of doing clinical trials in this patient population with hosts Dr. Tim Cripe (Nationwide Children's Hospital) and Dr. Robyn Dennis (Nationwide Children's Hospital).Dr. Brown is the Director, Pediatric Leukemia and Lymphoma Program and Associate Professor of Oncology and Assistant Professor of Pediatrics at The Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins School of Medicine. 

TWIPO #36 ~ Interview With Kathleen Neville, MD, on Pediatric Drug Development

January
27, 2014
New York, NY -- This Week in Pediatric Oncology
(TWiPO), the first podcast focusing on pediatric cancer research, announced
that Kathleen Neville,MD, from Children's Mercy Hospital in Kansas City, is a
featured guest on its most recent episode. In this episode, Dr. Kathleen
Neville talks about the challenges of drug development in pediatric cancer with
with host Dr. Tim Cripe (Nationwide Children's Hospital).
Kathleen Neville is the Director of
Experimental Therapeutics in the pediatric cancer program at Children's Mercy
Hospital in Kansas City. She is an Associate Professor of Pediatrics in the
division of pediatric clinical pharmacology, medical toxicology and
hematology-oncology at the University of Missouri-Kansas City School of
Medicine. She is also the chair of the education committee of the American
Society for Clinical Pharmacology and Therapeutics, and a consultant on FDA
pediatric advisory committee, and serves on the FDA Pediatric Oncology
Subcommittee of the Oncologic Drugs Advisory Committee.

TWIPO #35 ~ Interview With Robert Johnson, PhD

December
02, 2013
New York, NY -- This Week in Pediatric Oncology
(TWiPO), the first podcast focusing on pediatric cancer research, announced
that Robert Johnson, PhD, is a featured guest on its most recent episode, In
this episode, Dr. Johnson speaks with host Dr. Tim Cripe (Nationwide Children's
Hospital) and co-hosts Dr. Robyn Dennis (Nationwide Children's Hospital and Dr.
Lionel Chow (Cincinatti Children's) about the third most common type of brain
tumor in children, ependymomas.
Robert A. Johnson, PhD, is a principal
investigator at The Research Institute at Nationwide Children’s Hospital and an
Assistant Professor of Pediatrics at The Ohio State University College of
Medicine. The primary focus of the Johnson laboratory is the development of
novel therapies for the treatment of ependymoma, the third most common
pediatric brain tumor, by identifying and targeting the genetic changes
responsible for the formation of the disease.

TWIPO #34 ~Interview With Dr. Nancy Ratner

November
14, 2013
New York, NY -- This Week in Pediatric Oncology
(TWiPO), the first podcast focusing on pediatric cancer research, announced
that Nancy Ratner, PhD, is a featured guest on its most recent episode, In this
episode, Dr. Ratner speaks with host Dr. Tim Cripe (Nationwide Children's
Hospital) and co-host Dr. Robyn Dennis (Nationwide Children's Hospital).
Dr. Ratner is interested in understanding
mechanisms of peripheral nerve tumor (neurofibroma) formation in
Neurofibromatosis type 1 (NF1), a common inherited disorder in which children
are predisposed to cancer of the nervous system, to learning problems, bone
disorders, and other cancers. She identified EGFR as a potential therapeutic
target in NF1 peripheral nerve tumorigenesis, and has developed cell culture
and mouse models of NF1 nerve tumorigenesis. Her laboratory has also used
analysis of gene expression to identify critical genes in neurofibroma and
their malignant derivatives, MPNST.

Dr. Ratner is currently a professor in the Department of Pediatrics, Cincinnati
Children’s Hospital, University of Cincinnati, and the program leader for
Cancer Biology and Neural Tumors Program in the Cancer and Blood Disorders
Institute where she holds the Beatrice C. Lampkin Endowed Chair in Cancer
Biology and serves as PI of the NINDS P50 “Cincinnati Center in NF Research.”

TWIPO #33 ~Effective Advocacy with Gavin Lindberg

October
31, 2013
New York, NY—This Week in Pediatric Oncology
(TWiPO), the first podcast focusing on pediatric cancer research, announced
that Gavin Lindberg is a featured guest on its most recent episode, entitled
Effective Advocacy. In this episode, Mr. Lindberg speaks with host Dr. Tim Cripe
(Nationwide Children’s Hospital), and co-host Dr. Robyn Dennis (Nationwide
Children’s Hospital), about his work to increase funding for childhood cancer
research.
Mr. Lindberg is the President and Co-Founder of
The Evan’s Victory Against Neuroblastoma (EVAN) Foundation, which was
established in memory of his only child Evan Lindberg. Evan bravely battled
neuroblastoma for four years before passing away at the age of 7 in 2010. The
Foundation funds research aimed at fostering new therapies for children with
neuroblastoma, and sponsors patient-wellness programs for childhood cancer
patients enduring long and difficult stays in the hospital.
While his son was in treatment, Mr. Lindberg
served as the founding president of the Band of Parents, an organization that
raised over $1 million to develop a new humanized antibody for neuroblastoma
currently used at Memorial Sloan-Kettering Cancer Center, in New York City. Mr.
Lindberg and his wife Wendy also work to increase awareness of neuroblastoma
among policymakers in Washington, DC and have successfully advanced new
opportunities for federal support of neuroblastoma research within the
Department of Defense.