This Week in Pediatric Oncology

Solving Kids' Cancer explores new advances in childhood cancer with host Dr. Timothy Cripe from Nationwide Children's Hospital

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Episodes

Thursday Jan 06, 2022

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/uk1dxJe3VoY
Hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, meet with Dr. Elias Sayour from the University of Florida. While many are familiar with mRNA due to its COVID-19 vaccine application, Dr. Sayour discusses mRNA within the pediatric brain tumor landscape - including preclinical work, its delivery & distribution, as well as promising future opportunities for pediatric cancer patients.
Have any thoughts? Questions? Ideas for future topics? Email us at TWIPO@solvingkidscancer.org.
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Thursday Dec 02, 2021

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/7NAibEpTA0w
Hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, are joined by Dr. Mariella Filbin from Dana-Farber Cancer Institute/Boston Children's Hospital. Dr. Filbin discusses her expertise within DIPG including transcriptomics and epigenomics, as well as what is on the horizon for research - both challenging and exciting advances.
Have any thoughts? Questions? Ideas for future topics? Email us at TWIPO@solvingkidscancer.org.
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Want to listen to TWIPO's past episodes? Visit www.solvingkidscancer.org/podcast

Thursday Nov 04, 2021

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/Fd1flMgbfLw
Listen in as our hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, are joined in this episode by Dr. Lisa Diller from Dana-Farber/Boston Children's Cancer and Blood Disorders Center. Dr. Diller discusses the possibilities of genetic testing for pediatric cancer predisposition syndromes in newborn screening programs, but with uncertain benefits and costs. She recently authored a paper exploring mathematical modeling of a screening program for cost and benefit.
You can read her full paper here: https://pubmed.ncbi.nlm.nih.gov/33767345/

Monday Aug 30, 2021

WATCH THE VIDEO WEBCAST HERE: https://www.youtube.com/watch?v=nJZYz1XrsyY
Hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, are joined in this episode by Dr. Andras Heczey from Texas Children's Hospital/Baylor College of Medicine. Listen in as they discuss Dr. Heczey's expertise & research in utilizing Natural Killer (NK) T-cells for pediatric immunotherapy treatment and the process of doing so.
Have any thoughts? Questions? Ideas for future topics? Email us at TWIPO@solvingkidscancer.org.
Subscribe to TWIPO to get notifications of new uploads.
Want to listen to TWIPO's past episodes? Visit www.solvingkidscancer.org/podcast

Thursday Jul 29, 2021

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/zZiE19fhzQQ
Tune in to the latest TWiPO episode as hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, meet with Prof. Andy Pearson and Prof. Lou Chesler to discuss the ACCELERATE forums; Prof. Pearson & Prof. Chesler played pivotal roles in the start of the ALKi Pediatric Strategy Forum. Listen in as they discuss their experiences from the very first meeting, how topics are chosen, and the importance of bringing together key people from different industries. The ACCELERATE international platform provides a transparent forum to discuss and address, in a timely fashion, overarching issues in the development of innovative anticancer medicines for children and adolescents with cancer.
To learn more about ACCELERATE, please visit: https://www.accelerate-platform.org/

Monday Jun 28, 2021

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/PbNS-yFDTzA
Hosts Dr. Timothy Cripe & Dr. Brenda Weigel are joined by Dr. Samuel Blackman to discuss biotech solutions for pediatric cancer drug development. Dr. Blackman is the Co-Founder and Chief Medical Officer of Day One Biopharmaceuticals located in South San Francisco, CA. Tune in as Dr. Blackman discusses his career journey, the origins of Day One, and the challenges in pediatric cancer drug development today.
To learn more about Day One Biopharmaceuticals, go to https://dayonebio.com/.
Have any thoughts? Questions? Ideas for future topics? Email us at TWIPO@solvingkidscancer.org. Subscribe to TWIPO to get notifications of new uploads.
Want to listen to TWIPO's past episodes? Visit www.solvingkidscancer.org/podcast

Friday May 28, 2021

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/OSftR6JhEtY
As Brain Tumor Awareness Month draws to a close, we bring you a new TWIPO episode on the subject. Hosts Dr. Timothy Cripe & Dr. Brenda Weigel are joined by Dr. Gregory Friedman from the University of Alabama in Birmingham to discuss his recently published paper “Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas.” Listen in as Dr. Friedman discusses the findings of this phase 1 clinical trial and the progress of oncolytic virotherapy in pediatric brain tumors.
You can access the abstract to Dr. Friedman's paper here: https://pubmed.ncbi.nlm.nih.gov/33838625/
Have any thoughts? Questions? Ideas for future topics? Email us at TWIPO@solvingkidscancer.org. Subscribe to TWIPO to get notifications of new uploads.
Want to listen to TWIPO's past episodes? Visit www.solvingkidscancer.org/podcast

Friday May 14, 2021

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/TEFcsd5lt1A
In recognition of Brain Tumor Awareness Month, TWIPO hosts Dr. Timothy Cripe and Dr. Brenda Weigel are joined by Dr. Stergios Zacharoulis of Columbia University Irving Medical Center (CUIMC), where he initiated a novel drug delivery program for pediatric brain tumors. Listen in as Dr. Zacharoulis discusses different delivery methodologies being explored and developed that bypass the blood brain barrier.
 
Have any thoughts? Questions? Ideas for future topics? Email us at TWIPO@solvingkidscancer.org. Subscribe to TWIPO to get notifications of new uploads. 

Friday Mar 12, 2021

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/R_GyqL36_dg
Hosts Dr. Tim Cripe and Dr. Brenda Weigel met with Dr. Gilles Vassal and Patricia Blanc on the ACCELERATE Platform: Innovation for Children and Adolescents with Cancer. Dr. Gilles Vassal is the head of Clinical Research at Institut Gustave Roussy in Villejuif, France & he is also the Chair for the ACCELERATE Steering Committee. Patricia Blanc is the President & Founder of the Imagine for Margo Foundation and serves as a Patient Advocate for ACCELERATE. Listen in to hear how the ACCELERATE platform came to be & the advances they are making within the childhood cancer research landscape. The ACCELERATE international platform provides a transparent forum to discuss and address, in a timely fashion, overarching issues in the development of innovative anticancer medicines for children and adolescents with cancer.
To learn more about ACCELERATE, please visit: https://www.accelerate-platform.org/
 

Friday Jan 29, 2021

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/io13HbVwtbI
Hosts Tim Cripe and Brenda Weigel welcome Dr. Chris Dandoy, from Cincinnati Children's Hospital, and parent advocate, Sarah Moore, to discuss the current research on TA-TMA and the implications for children undergoing stem cell transplant (SCT) for pediatric cancers, notably tandem SCTs for high-risk neuroblastoma.
 
Dr. Dandoy is Assistant Professor of Clinical Pediatrics in Bone Marrow Transplantation and Immune Deficiency at Cincinnati Children’s Hospital Medical Center and this episode discussion focused on four recently published papers by Dr. Dandoy describing effects, incidence, risk factors, screening, and treatment of this serious complication of transplants. Sarah Moore also shared her perspective as a mother to a child who recently underwent tandem SCT for high-risk neuroblastoma, and has been active in parent forums discussing the incidence and implications of TA-TMA and sharing evidence-based information.
 
Have any thoughts? Questions? Ideas for future topics? Email us at TWIPO@solvingkidscancer.org.
 
Subscribe to TWIPO to get notifications of new uploads.
 
Want to listen to TWIPO's past episodes? Visit www.solvingkidscancer.org/podcast

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