This Week in Pediatric Oncology

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Entries Tagged as 'childhood cancer'

TWiPO #73 - Dr. Peter Adamson comes back to talk about progress, the drug shortage, families’ impact, and so much more

March 2nd, 2018 · Comments

Host, Dr. Timothy Cripe from Nationwide Children's Hospital, along with his co-hosts - Dr. Ryan Roberts, Dr. Nilay Shah, Dr. Keri Streby, and Dr. Mark Ranalli, interview Dr. Peter Adamson from Children's Hospital of Philadelphia. Dr. Adamson was previously interviewed back in 2011, in Podcast #9, and they discuss the progress that has been made since then. Dr. Adamson goes on to talk about private-public partnerships, families' impact on the field, the drug shortage problem, and much more. Tune in to this podcast to learn more about all of these interesting topics.

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Tags: cancer · childhood cancer · Advancement in Cancer Research · oncology

TWiPO #72 - Dr. Eugene Hwang discusses his work with immunotherapy and pseudo-progression

February 1st, 2018 · Comments

Hosts, Dr. Timothy Cripe, Dr. Keri Steby, Dr. Ryan Roberts, and Dr. Jonathan Finlay from Nationwide Children's Hospital are joined by Dr. Eugene Hwang, who is a pediatric hematologist-oncologist at the Children's National Medical Center in Washington D.C. Dr. Hwang discusses his work with immunotherapy and pseudo-progression, as well as explains the basics of a solid tumor clinical trial he created in conjunction with Dr. Catherine Bollard. Listen in to learn more.

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Tags: cancer · pediatric cancer · childhood cancer · brain tumor · immunotherapy · clinical trials

TWiPO #71 - Interview with Nancy Goodman, Founder and Executive Director of Kids v. Cancer

December 21st, 2017 · Comments

Host, Dr. Timothy Cripe, from Nationwide Children's Hospital in Columbus, Ohio had the honor of interviewing Nancy Goodman, Founder and Executive Director of Kids v. Cancer in Washington DC.

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Tags: children · pediatric cancer · childhood cancer · medulloblastoma · research · profile interview

TWiPO #68 - Dr. Dean Lee discusses his experience with T-cell CARs

November 15th, 2017 · Comments

Host Dr. Timothy Cripe and Dr. Nilay Shah, from Nationwide Children's Hospital in Columbus, Ohio, is joined by Dr. Dean Lee to discuss their experience with T-cell CARs (Chimeric Antigen Receptors).

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Tags: children · pediatric cancer · childhood cancer

TWiPO #67 - Interview with Dr. Mitchell Cairo

November 15th, 2017 · Comments

Hosts Dr. Nilay Shah, Dr. Ryan Roberts, and Dr. Keri Streby from Nationwide Children’s Hospital in Columbus, Ohio, sit down with Dr. Mitchell Cairo to discuss his experiences within the pediatric cancer research sector.

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Tags: children · pediatric cancer · childhood cancer · T-cell · research

TWIPO #66 - Interview with Dr. Rani George

October 2nd, 2017 · Comments

Host Dr. Ryan Roberts, from Nationwide Children's Hospital in Columbus, Ohio, is joined by Dr. Rani George to discuss her experience with studying neuroblastoma and how she got involved in the field of oncology. George discusses her thoughts on what is needed to progress pediatric cancer research - including relapse biopsies, understanding the biology, and, of course, funding. As Dr. Roberts says, what we need is, "...more time, more patience, and more funding."  Please send questions and comments to TWiPO@solvingkidscancer.org 

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Tags: cancer · children · pediatric cancer · childhood cancer · drug development · neuroblastoma · research · immunotherapy · Advancement in Cancer Research

TWiPO #65 - Interview with Dr. Brenda Weigel

October 2nd, 2017 · Comments

In this podcast, co-Hosts Dr. Robyn Dennis and Dr. Ryan Roberts had the honor of interviewing Dr. Brenda Weigel, Director of the Division of Pediatric Hematology/Oncology at the University of Minnesota. Dr. Weigel discusses her “serendipitous” background story of how she became involved in childhood oncology, as well as talks about the challenges the field faces with managing new cancer therapies. But, despite the challenges, she is hopeful that we are moving away from chemotherapy treatments into an era of cancer therapies that “hopefully, has the potential to cure the cancers and improve the quality of life”. 

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Tags: cancer · pediatric cancer · childhood cancer · drug development · research · immunotherapy · Advancement in Cancer Research

TWiPO #64 - Interview with Dr. Lars Wagner

July 17th, 2017 · Comments

It’s an exciting time to be part of the childhood cancer research community, and this interview was focused on career advice for those interested in childhood oncology and research. The availability of genomic profiling of tumors, targeted agents and the development of new immunotherapies are increasing the opportunities available to patients today. This lively discussion addresses the importance of preclinical data, predictive biomarker studies and the measurement of responses, with specific references to Dr. Wagner’s experience with studying irinotecan.   Dr. Wagner also answered questions about radiomics and how this imaging trend can provide more insights for enhanced radiology reporting.

Please send questions and comments to TWiPO@solvingkidscancer.org 

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Tags: cancer · pediatric cancer · childhood cancer · drug development · sarcoma · immunotherapy · young adults · Advancement in Cancer Research

TWiPO #63 - Dr. Javier Blanco discusses chemotherapy late effects and cardio-toxicity

July 17th, 2017 · Comments

Co-Hosts Dr. Timothy Cripe and Dr. Randal Olshefski (Nationwide Children's Hospital), interview Dr. Javier Blanco, Associate Professor at the Department of Pharmaceutical Sciences at SUNY Buffalo, about the late effects of chemotherapy.  In this podcast, the participants discuss the role that chemotherapy, such as doxorubicin and other anthracycline drugs, often play in increasing cardio-toxicity.

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Tags: cancer · childhood cancer · drug development · clinical trials · cardiotoxicity

TWiPo #59 ~ Interview with Dr. Sajid Qureshi

October 17th, 2016 · Comments

Host Dr. Timothy Cripe and co-Host Nilay Shah interview Dr. Sajid Qureshi, a professor of Pediatric Oncology at the Tata Memorial Center, Mumbai, India. Dr. Qureshi is an Executive Committee Member of the International Society of Pediatric Surgical Oncology (IPSO). In this episode Dr. Qureshi provides a fascinating, first-hand glimpse into the successes and challenges of delivering quality care to larger, as well as remote, pediatric cancer populations. The episode concludes with Dr. Qureshi's thoughts on how international research collaboration could provide access to relapsed children worldwide.

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Tags: families · cancer · children · pediatric cancer · childhood cancer · drug development · neuroblastoma · research · brain tumor · clinical trials · Advancement in Cancer Research

TWiPO #58 ~ Interview with Dr. Damon Reed

October 17th, 2016 · Comments

TWiPO Host Dr. Timothy Cripe, with co-hosts Dr. Nilay Shah and Dr. Bhuvana Setty welcome Dr. Damon Reed, Director of the Adolescent and Young Adult Program at Moffitt Cancer Center and Leader of the Pediatric Cancer Foundation's pediatric phase I consortium, the Sunshine Project. Dr. Reed shares his view points on how we can improve and accelerate the current trajectory with regard to pediatric therapy development. 

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Tags: families · cancer risk · cancer · children · pediatric cancer · childhood cancer · drug development · neuroblastoma · medulloblastoma · sarcoma · research · brain tumor · immunotherapy · clinical trials · Advancement in Cancer Research

TWIPO # 57 Interview with Dr. Elizabeth Lawlor

October 6th, 2016 · Comments

TWIPO hosts Dr. Timothy Cripe and Dr. Nilay Shah (Nationwide Children's Hospital) along with guest host Dr. Ryan Roberts (Nationwide Children's Hospital), interview Dr. Elizabeth Lawlor who is a Professor of Pediatric Oncology at University of Michigan and the Director of the Cancer Biology Training Program at University of Michigan Health System. Dr. Lawlor, a Ewing Sarcoma specialist, discusses new approaches to the cellular eco-system of tumors and provides commentary on the growing landscape for women in science.

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Tags: cancer · children · pediatric cancer · childhood cancer · sarcoma · research · immunotherapy · young adults · Ewing Sarcoma · Epigenetics

TWIPO #56 ~ Interview with Dr. Mark Hatley

September 6th, 2016 · Comments

On today's podcast, TWIPO host Dr. Timothy Cripe (Nationwide Children’s Hospital) and co-host Dr. Ryan Roberts (Nationwide Children’s Hospital) interview Dr. Mark Hatley (St. Jude Children's Research Hospital). Dr. Hatley discusses how he got into the field of Biological Chemistry in Oncology. Also Dr. Hatley gives an indepth explaination about his research in G-Proteins.

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Tags: cancer · children · pediatric cancer · childhood cancer · drug development · neuroblastoma · medulloblastoma · research · brain tumor · immunotherapy · clinical trials · Advancement in Cancer Research

TWiPO #55 ~ Interview with Dr. Chrystal Louis

June 3rd, 2016 · Comments

On this episode of TWiPO podcast Dr. Timothy Cripe (Nationwide Children’s Hospital) and co-host, Dr. Nilay Shah (Nationwide Children’s Hospital) and Dr. Keri A. Streby (Nationwide Children's Hospital) interview Dr. Chrystal Louis (Assistant Professor, Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine.) Dr. Louis talks to the hosts about her role in both the academic and industry side of oncology. 

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Tags: cancer · children · pediatric cancer · childhood cancer · drug development · research · brain tumor · clinical trials · Advancement in Cancer Research

TWiPO #54 ~ Interview with Dr. Kim Kramer

June 3rd, 2016 · Comments

On today's TWiPO Podcast host Dr. Timothy Cripe (Nationwide Children’s Hospital) and co-host, Dr. Nilay Shah (Nationwide Children’s Hospital) interview Dr. Kim Kramer (Pediatric Oncologist of Memorial Sloan Kettering.) In this interview they discuss a new cutting edge therapy for treating brain tumors, which involves targeting the tumor intravenously just like any other tumor.

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Tags: families · cancer · children · pediatric cancer · childhood cancer · drug development · brain tumor

TWiPO #53 ~ Interview with Linda McAllister-Lucas

April 13th, 2016 · Comments

On today's podcast TWiPO host Dr. Timothy Cripe (Nationwide Children’s Hospital) and co-hosts, Dr. Nilay Shah (Nationwide Children’s Hospital) and Dr. Robyn Dennis (Nationwide Children’s Hospital) Interview Dr. Linda McAllister-Lucas (Chief of Service, Hematology/Oncology of Children's Hospital of Pittsburgh, Associate Professor of Pediatrics, University of Pittsburgh School of Medicine. In their discussion Dr. McAllister-Lucas talks about her research on MALT1 Lymphoma and how this research could advance the field of oncology 

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Tags: cancer risk · cancer · children · pediatric cancer · childhood cancer · drug development · research · brain tumor · Advancement in Cancer Research

TWIPO #52 ~ Interview with Dr. James Geller

December 9th, 2015 · Comments

On this TWiPO episode hosts, Dr. Timothy Cripe and Dr. Nilay Shah (Nationwide Children’s Hospital) interview Dr. James Geller (Medical Director at Kidney and Liver Tumors Program, Co-Medical Director at Retinoblastoma Program, Associate Director at Global Cancer Programs, Associate Professor at UC Department of Pediatrics.) Dr. James Geller was one of the original TWiPO members back in 2010. Today Dr. Geller talks about the battle to get access to potential drugs (Ex. Lorvotuzumab [IMGN901]) that can be beneficial to treating pediatric cancers.

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Tags: cancer · children · pediatric cancer · childhood cancer · drug development · neuroblastoma

TWIPO #50 ~ Interview With Dr. Jonathan Finlay

May 8th, 2015 · Comments

In this most recent TWiPO podcast hosted by Dr. Timothy Cripe (Nationwide Children’s Hospital), he interviews Dr. Jonathan Finlay (Program Director of Neuro-Oncology at Nationwide Children’s Hospital) about sparked in research interest in brain tumors. One of Dr. Finlay’s mentors, helped launch a new treatment, which was able to rescue a proportion of newly diagnosed children who failed conventional chemotherapy, radiation, and surgery. That novel treatment is now a growing method of treating medulloblastoma.

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Tags: pediatric cancer · childhood cancer · medulloblastoma · profile interview · brain tumor

TWIPO #39 ~ Declining Childhood Cancer Mortality & CAR123 T-cells

July 10th, 2014 · Comments

New York, NY -- In the most recent episode of This Week in Pediatric Oncology (TWiPO), the first podcast focusing on pediatric cancer research, co-hosts Dr. Timothy Cripe (Nationwide Children's Hospital), Dr. Robyn Dennis (Nationwide Children's Hospital), Dr. Andy Kolb (A.I. Dupont) and Dr. Lionel Chow (Cincinatti Children's) discuss two recent papers on the declining mortality rate in childhood and adolescent cancers and a pre-clinical study using CAR123 T-cells.


Saar Gill, Sarah K. Tasian, Marco Ruella, Olga Shestova, Yong Li, David L. Porter, Martin Carroll, Gwenn Danet-Desnoyers, John Scholler, Stephan A. Grupp, Carl H. June, and Michael Kalos. Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor–modified T cells. Blood. 2014, 10, April. http://www.ncbi.nlm.nih.gov/pubmed/24596416

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Tags: childhood cancer · leukemia

TWIPO #38 ~ Interview with John Goldberg, MD, on Phase I Clinical Trials

March 11th, 2014 · Comments

March 11, 2014

New York, NY -- This Week in Pediatric Oncology (TWiPO), the first podcast focusing on pediatric cancer research, announced that John Goldberg, MD, from The Sylvester Comprehensive Cancer Center at the University of Miami, is a featured guest on its most recent episode. In this episode, Dr. Golberg talks about the challenges of phase I pediatric cancer clinical trials with hosts Dr. Tim Cripe (Nationwide Children's Hospital), Dr. Robyn Dennis (Nationwide Children's Hospital), and Mark Ranalli, MD (Nationwide Children's Hospital).

Dr. Goldberg is an Assistant Professor of Pediatrics and the Director of the Pediatric Oncology Early Phase Clinical Trials Program at The Sylvester Comprehensive Cancer Center, the University of Miami.

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Tags: pediatric cancer · childhood cancer · clinical trials