This Week in Pediatric Oncology
neuroblastoma
Episodes
Tuesday Sep 06, 2016
Tuesday Sep 06, 2016
On today's podcast, TWIPO host Dr. Timothy Cripe (Nationwide Children’s Hospital) and co-host Dr. Ryan Roberts (Nationwide Children’s Hospital) interview Dr. Mark Hatley (St. Jude Children's Research Hospital). Dr. Hatley discusses how he got into the field of Biological Chemistry in Oncology. Also Dr. Hatley gives an indepth explaination about his research in G-Proteins.
Wednesday Dec 09, 2015
Wednesday Dec 09, 2015
On this TWiPO episode hosts, Dr. Timothy Cripe and Dr. Nilay Shah (Nationwide Children’s Hospital) interview Dr. James Geller (Medical Director at Kidney and Liver Tumors Program, Co-Medical Director at Retinoblastoma Program, Associate Director at Global Cancer Programs, Associate Professor at UC Department of Pediatrics.) Dr. James Geller was one of the original TWiPO members back in 2010. Today Dr. Geller talks about the battle to get access to potential drugs (Ex. Lorvotuzumab [IMGN901]) that can be beneficial to treating pediatric cancers.
Monday Apr 20, 2015
Monday Apr 20, 2015
TWiPO host Dr. Nilay Shah (Nationwide Children’s Hospital) interviews Dr. Michael D. Hogarty, MD, an attending physician in the Division of Oncology at The Children's Hospital of Philadelphia. Dr. Hogarty recalls his efforts in finding a new way of tackling neuroblastoma by sending 17,000 tumor samples around the world. In this short interview, he discusses his current work in the lab, which involves testing the MYC gene found in children with high-risk neuroblastoma.
Monday Mar 30, 2015
Monday Mar 30, 2015
TWiPo co-hosts Dr. Keri Stretby
(Nationwide Children’s Hospital) and
Dr. Nilay Shah (Nationwide Children’s Hospital) interview Hiroyuki Shimada, MD,
PhD, Professor of Clinical Pathology at the Children’s Hospital of Lost
Angeles. Dr. Shimada developed the Shimada neuroblastoma classification system
for neuroblastoma, which was the basis of The International Neuroblastoma
Pathology Classification and now The International Neuroblastoma Risk Group
classification system.
Monday Mar 30, 2015
Monday Mar 30, 2015
TWiPO host Dr. Nilay Shah (Nationwide Children’s Hospital) interviewed Susan L. Cohn, MD, a Professor of Pediatrics, Dean of Clinical Research at the University of Chicago at the ANR meeting in Cologne, Germany last year for this episode of This Week in Pediatric Oncology. Dr. Cohn is a highly respected expert in pediatric cancers and blood diseases. She is a leading authority on neuroblastoma and actively researching several aspects of neuroblastoma. Her research has received generous support from the National Institutes of Health/National Cancer Institute and the National Institute of Neurological Disorders and Stroke. Dr. Shaw and Dr. Cohn discuss the future of neuroblastoma research and clinical trial design to create more effective treatment options for children with high-risk disease.
Monday Nov 10, 2014
Monday Nov 10, 2014
In the most recent
episode of This Week in Pediatric Oncology (TWiPO), the first podcast focusing
on pediatric cancer research, co-hosts Dr. Keri Stretby (Nationwide Children’s
Hospital) and Dr. Nilay
Shah (Nationwide Children’s Hospital), caught up with Professor Michelle
Haber (Executive Director at Children’s Cancer Institute in Australia and Professor Andrew Pearson of
the Cancer Research UK. In this 26-minute podcast, both researchers
discuss the future of neuroblastoma, specifically looking at precision medicine,
the role of gene sequencing and the role of international collaboration to
bring new therapies into the clinic.
Wednesday Jul 23, 2014
Wednesday Jul 23, 2014
New York – This Week in Pediatric Oncology presents the third and final interview from the recent Advances in Neuroblastoma Research meeting, which was held in Cologne, Germany, in May. Co-hosts Dr. Nilay Shah (Nationwide Children’s Hospital) and Dr. Keri Stretby (Nationwide Children’s Hospital) talk with Frank Berthold, ANR2014 Local Chairman, to discuss meeting highlights in the short, 18-minute interview.
Tuesday Jul 15, 2014
Tuesday Jul 15, 2014
New York – This Week in Pediatric Oncology presents the second in a series of interviews from the recent Advances in Neuroblastoma Research meeting, which was held in Cologne, Germany, in May. Co-hosts Dr. Nilay Shah (Nationwide Children’s Hospital) and Dr. Keri Stretby (Nationwide Children’s Hospital) discuss MIBG therapy in treating children with high-risk neuroblastoma with Dr. Kate Matthay (UCSF Benioff Children's Hospital) and Dr. Gregory Yanik (C.S. Mott Children’s Hospital at the University of Michigan). In this 45-minute interview, both Drs. Matthay and Yanik, who have conducted extensive research in MIBG throughout their long careers, share their perspectives on what’s going on in the field now and opportunities to improve the therapy in the future.
Monday Feb 10, 2014
Monday Feb 10, 2014
May
07, 2012
In this interesting episode, host Dr. Tim Cripe
(Nationwide Children's) and co-hosts Dr. Lionel Chow (Cincinnati Children's),
Dr. Andy Kolb (AI DuPont), and Donna Ludwinski (Solving Kids' Cancer) quiz Dr
Paul Sondel and Dr. Ken DeSantes (both from University of Wisconsin - Madison)
on NK cells and the implications of KIR/KIR-ligand mismatch (killer
immunoglobulin-like receptor) with regard to immunotherapy treatment of
neuroblastoma.
References:
Delgado DC, Hank JA, Kolesar J, Lorentzen D, et
al. Genotypes of NK cell KIR receptors, their ligands, and Fcγ receptors in the
response of neuroblastoma patients to Hu14.18-IL2 immunotherapy. Cancer Res.
2010 Dec 1;70(23):9554-61. Epub 2010 Oct 8.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999644/
.
Venstrom JM, Zheng J, Noor N, Danis KE, et al.
KIR and HLA genotypes are associated with disease progression and survival
following autologous hematopoietic stem cell transplantation for high-risk
neuroblastoma. Clin Cancer Res. 2009 Dec 1;15(23):7330-4. Epub 2009 Nov 24.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788079/
.
Alderson KL, Sondel PM. Clinical cancer therapy
by NK cells via antibody-dependent cell-mediated cytotoxicity. J Biomed
Biotechnol. 2011;2011:379123. Epub 2011 May 24.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110303/
Monday Feb 10, 2014
Monday Feb 10, 2014
January
26, 2012In 2011 there were over 1300 new articles
published on neuroblastoma in the medical literature.
Join Dr. Tim Cripe and his co-host Dr. Lars
Wagner in a fast-paced, in-depth, and comprehensive survey of 18 of the most
important papers on neuroblastoma published in 2011. Dr. Cripe and Dr Wagner
explore and discuss the compelling evidence reported on a variety of topics,
including epidemiology, risk stratification, clinical trials, ALK mutation and
expression, new targets, and genetics.
All of the papers discussed are listed HERE with links to PubMed.
Please send all comments and questions to twipo@solvingkidscancer.org