This Week in Pediatric Oncology
clinical trials
Episodes
Thursday Jan 20, 2022
Thursday Jan 20, 2022
WATCH THE VIDEO WEBCAST HERE: https://youtu.be/AFmMxBeZOa4
Tune in as our hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, meet with Dr. Rimas Orentas - the Scientific Director of Caring Cross & a Professor from Seattle Children's Hospital. In this episode, Dr. Orentas discusses his expertise in cellular gene therapy - the accessibility, production, testing, and the importance of diversity and inclusion amongst research subjects.
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Thursday Jan 06, 2022
Thursday Jan 06, 2022
WATCH THE VIDEO WEBCAST HERE: https://youtu.be/uk1dxJe3VoY
Hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, meet with Dr. Elias Sayour from the University of Florida. While many are familiar with mRNA due to its COVID-19 vaccine application, Dr. Sayour discusses mRNA within the pediatric brain tumor landscape - including preclinical work, its delivery & distribution, as well as promising future opportunities for pediatric cancer patients.
Have any thoughts? Questions? Ideas for future topics? Email us at TWIPO@solvingkidscancer.org.
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Thursday Nov 04, 2021
Thursday Nov 04, 2021
WATCH THE VIDEO WEBCAST HERE: https://youtu.be/Fd1flMgbfLw
Listen in as our hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, are joined in this episode by Dr. Lisa Diller from Dana-Farber/Boston Children's Cancer and Blood Disorders Center. Dr. Diller discusses the possibilities of genetic testing for pediatric cancer predisposition syndromes in newborn screening programs, but with uncertain benefits and costs. She recently authored a paper exploring mathematical modeling of a screening program for cost and benefit.
You can read her full paper here: https://pubmed.ncbi.nlm.nih.gov/33767345/
Monday Aug 30, 2021
Monday Aug 30, 2021
WATCH THE VIDEO WEBCAST HERE: https://www.youtube.com/watch?v=nJZYz1XrsyY
Hosts, Dr. Timothy Cripe and Dr. Brenda Weigel, are joined in this episode by Dr. Andras Heczey from Texas Children's Hospital/Baylor College of Medicine. Listen in as they discuss Dr. Heczey's expertise & research in utilizing Natural Killer (NK) T-cells for pediatric immunotherapy treatment and the process of doing so.
Have any thoughts? Questions? Ideas for future topics? Email us at TWIPO@solvingkidscancer.org.
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Want to listen to TWIPO's past episodes? Visit www.solvingkidscancer.org/podcast
Friday May 28, 2021
Friday May 28, 2021
WATCH THE VIDEO WEBCAST HERE: https://youtu.be/OSftR6JhEtY
As Brain Tumor Awareness Month draws to a close, we bring you a new TWIPO episode on the subject. Hosts Dr. Timothy Cripe & Dr. Brenda Weigel are joined by Dr. Gregory Friedman from the University of Alabama in Birmingham to discuss his recently published paper “Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas.” Listen in as Dr. Friedman discusses the findings of this phase 1 clinical trial and the progress of oncolytic virotherapy in pediatric brain tumors.
You can access the abstract to Dr. Friedman's paper here: https://pubmed.ncbi.nlm.nih.gov/33838625/
Have any thoughts? Questions? Ideas for future topics? Email us at TWIPO@solvingkidscancer.org. Subscribe to TWIPO to get notifications of new uploads.
Want to listen to TWIPO's past episodes? Visit www.solvingkidscancer.org/podcast
Friday May 14, 2021
Friday May 14, 2021
WATCH THE VIDEO WEBCAST HERE: https://youtu.be/TEFcsd5lt1A
In recognition of Brain Tumor Awareness Month, TWIPO hosts Dr. Timothy Cripe and Dr. Brenda Weigel are joined by Dr. Stergios Zacharoulis of Columbia University Irving Medical Center (CUIMC), where he initiated a novel drug delivery program for pediatric brain tumors. Listen in as Dr. Zacharoulis discusses different delivery methodologies being explored and developed that bypass the blood brain barrier.
Have any thoughts? Questions? Ideas for future topics? Email us at TWIPO@solvingkidscancer.org. Subscribe to TWIPO to get notifications of new uploads.
Friday Mar 12, 2021
Friday Mar 12, 2021
WATCH THE VIDEO WEBCAST HERE: https://youtu.be/R_GyqL36_dg
Hosts Dr. Tim Cripe and Dr. Brenda Weigel met with Dr. Gilles Vassal and Patricia Blanc on the ACCELERATE Platform: Innovation for Children and Adolescents with Cancer. Dr. Gilles Vassal is the head of Clinical Research at Institut Gustave Roussy in Villejuif, France & he is also the Chair for the ACCELERATE Steering Committee. Patricia Blanc is the President & Founder of the Imagine for Margo Foundation and serves as a Patient Advocate for ACCELERATE. Listen in to hear how the ACCELERATE platform came to be & the advances they are making within the childhood cancer research landscape. The ACCELERATE international platform provides a transparent forum to discuss and address, in a timely fashion, overarching issues in the development of innovative anticancer medicines for children and adolescents with cancer.
To learn more about ACCELERATE, please visit: https://www.accelerate-platform.org/
Friday Jan 29, 2021
Friday Jan 29, 2021
WATCH THE VIDEO WEBCAST HERE: https://youtu.be/io13HbVwtbI
Hosts Tim Cripe and Brenda Weigel welcome Dr. Chris Dandoy, from Cincinnati Children's Hospital, and parent advocate, Sarah Moore, to discuss the current research on TA-TMA and the implications for children undergoing stem cell transplant (SCT) for pediatric cancers, notably tandem SCTs for high-risk neuroblastoma.
Dr. Dandoy is Assistant Professor of Clinical Pediatrics in Bone Marrow Transplantation and Immune Deficiency at Cincinnati Children’s Hospital Medical Center and this episode discussion focused on four recently published papers by Dr. Dandoy describing effects, incidence, risk factors, screening, and treatment of this serious complication of transplants. Sarah Moore also shared her perspective as a mother to a child who recently underwent tandem SCT for high-risk neuroblastoma, and has been active in parent forums discussing the incidence and implications of TA-TMA and sharing evidence-based information.
Have any thoughts? Questions? Ideas for future topics? Email us at TWIPO@solvingkidscancer.org.
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Want to listen to TWIPO's past episodes? Visit www.solvingkidscancer.org/podcast
Tuesday Dec 08, 2020
Tuesday Dec 08, 2020
WATCH THE VIDEO WEBCAST HERE: https://youtu.be/ANmLBfdVJYQ
Host Tim Cripe welcomes his new Co-Host, Dr. Brenda Weigel, to reflect on her career, leadership, and focus areas since her last interview on TWiPO in 2017. Dr. Weigel is the Director of the Division of Pediatric Hematology/Oncology at the University of Minnesota's Cancer Center, Chair of Developmental Therapeutics in the COG, and Chair of the Pediatric Early Phase Clinical Trials Network (PEP-CTN) for the NCI.
She is at the epi-center for getting new drugs into the clinic for children with cancer and shares her perspective on the impact of the game-changing RACE Act that was implemented in 2020. She weighs in on prioritization of same-class drugs, evolving clinical trial design for small patient populations, and the increasing need for international collaboration in conducting clinical trials. She also discusses the importance of quality-of-life assessments and patient-reported outcomes and shares the efforts ongoing in the US and EU regulatory landscape to advance drug development for children with cancer.
Wednesday Sep 30, 2020
Wednesday Sep 30, 2020
WATCH THE VIDEO WEBCAST HERE: https://youtu.be/p7rMXwAu3qA
This Week in Pediatric Oncology (TWIPO) - our host, Timothy Cripe, MD, meets with the new Chair of the Children's Oncology Group (COG), Douglas Hawkins, MD, to discuss the future of the pediatric cancer research landscape.
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